ArticleThe Journal of clinical and aesthetic dermatology2026
A Randomized, Double-blind, Split-face Trial Evaluating the Safety and Efficacy of a Serum Containing Plant Adaptogens Versus Moisturizing Lotion Pre- and Post-fractional Laser in Patients with Mild-to-moderate Photodamage.
Article in The Journal of clinical and aesthetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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Authors and funding
2 authors.
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Abstract
objectiveWe aimed to evaluate the safety and efficacy of a serum containing plant adaptogens (MYS) compared to a moisturizing lotion (ML) pre- and post-laser treatment.
methodsA double-blind, split-face controlled study enrolled women with mild-to-moderate photodamaged skin. Participants were randomized to twice-daily application of MYS and ML to one side of their face and ML only to the opposite side two weeks prior to and 10 days following a single, non-ablative fractional laser treatment. Tolerability and global skin healing were assessed immediately post-procedure and on Days 1, 2, 4, 7, and 10. Global skin quality (the total sum of scores for erythema, dullness, rough skin texture, pores, and uneven pigmentation) was calculated at baseline, Week 2 (pre-procedure/skincare only), and Day 10 (post-procedure).
resultsFifteen participants completed the study (mean age: 52 years). Significantly less dryness occurred on the MYS vs. the ML side of the face on Days 1 and 2 (
conclusionTwice-daily application of a serum containing plant adaptogens before and after non-ablative fractional laser treatment demonstrated significant reductions in dryness and erythema, and improvements in global skin healing and skin quality compared to ML.
Indexed as
Identifiers
41648096PMC12872256What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.