ArticleIntestinal Failure (New York, N.Y.)
Pilot study of a topical magnesium preparation to treat hypomagnesaemia in patients with an ileostomy.
Article in Intestinal Failure (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Patients with a high output ileostomy often have hypomagnesaemia. This study aimed to determine if a magnesium chloride hexahydrate spray would maintain or increase serum magnesium in ileostomy patients with hypomagnesaemia. Methods: Outpatients with an ileostomy and having chronic hypomagnesaemia (serum magnesium <0.66 mmol/L) applied 10 sprays of magnesium chloride hexahydrate spray twice daily for 6 weeks (150 mg/day, 6.2 mmol magnesium). Serum and whole cell Mg Results: 6 patients completed the study, all had normal vitamin D levels (>45 nmol/L), and 5 of 6 had urinary magnesium concentrations below 0.28 mmol/L. 2 patients had a rise in serum Mg Conclusions: A topical magnesium chloride hexahydrate spray maintains or improves serum magnesium levels in patients with an ileostomy and hypomagnesaemia and prevents muscle cramps. Clinical trial number: RD13-045.
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