Evidence map›Paper›PMID 41648074›Full record

ArticlePregnancy (Hoboken, N.J.)2026

Comprehensive blood pressure management to improve early postpartum blood pressure parameters: A randomized controlled trial.

Alexandra J D Phelps, Jinyuan Liu, Kathryn J Lindley, Julia C Phillippi, Megan Webb, Loveis Jackson, Lilly He, Ashanti E Griggs-Cooks, Neha Dudipala, Soha S Patel and 2 more

Abstract read
In one paragraph

Article in Pregnancy (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alexandra J D PhelpsDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0002-6560-4249
Jinyuan LiuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.ORCID 0000-0001-6689-8245
Kathryn J LindleyDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Julia C PhillippiVanderbilt, University School of Nursing, Nashville, Tennessee, USA.ORCID 0000-0002-6549-094X
Megan WebbDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Loveis JacksonDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Lilly HeDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Ashanti E Griggs-CooksDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Neha DudipalaDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Soha S PatelDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Etoi GarrisonDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Sarah S OsmundsonDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Comprehensive Postpartum Management for Women with Hypertensive Disorders of PregnancyR21NR020857 · NINR · VANDERBILT UNIVERSITY MEDICAL CENTER · PI OSMUNDSON, SARAH SCHEIDERICH · 2022 to 2023
$488k
NCATS NIH HHS UL1 TR000445NINR NIH HHS R21 NR020857
6 · The paper itself

Abstract

Introduction: Adherence to blood pressure (BP) evaluation 7-10 days after pregnancy complicated by hypertension is poor. Current guidelines for postpartum BP control are more liberal than those for nonpregnant individuals. Our objective was to determine whether a comprehensive BP management program and tight BP control improve BP outcomes at 7-10 days postpartum compared with clinician-directed management and standard targets. Methods: Postpartum patients with chronic or gestational hypertension, preeclampsia/eclampsia, or HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome were randomized simultaneously to two interventions (four arms total): (1a) comprehensive management with remote BP monitoring and algorithm-based treatment, (1b) clinician-directed management at the primary obstetric provider's discretion, and (2a) tight (<140/90 mmHg) versus (2b) standard (<150/100 mmHg) BP control. Outcomes were measured at 7-10 days postpartum; the primary outcome was in-office BP evaluation and secondary outcomes included BP ascertainment (remote or in-person), BP change from baseline, antihypertensive medication initiation, any BP ≥140/90 mmHg or ≥160/110 mmHg, and all-cause emergency department visits or hospital readmissions. Results: From May 9, 2023 to August 1, 2024, 334 of 660 eligible participants were randomized. There was no difference for the primary outcome of in-person BP visit attendance between the comprehensive and clinician-directed management interventions (62.5% [ Conclusion: A comprehensive postpartum BP management program with coaching and remote monitoring did not improve in-person BP visit attendance at 7-10 days postpartum but did increase odds of patients reporting any BP to a clinician. Findings from the secondary outcomes suggest that a tight BP target combined with the comprehensive BP management program reduced systolic BP and increased the odds of initiating new antihypertensives by 10 days postpartum.

Indexed as

blood pressurecomprehensive blood pressure managementhypertensionhypertensive disorders of pregnancypostpartumremote blood pressure monitoring

Identifiers

PMID41648074
PMCPMC12872160

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.