ArticleMedical research archives2025
Head Up Cardiopulmonary Resuscitation: Novel Physiological Discoveries and Latest Clinical Outcomes.
Article in Medical research archives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Despite decades of research, survival rates following cardiac arrest remain dismal. The recent use of pressure-volume (PV) loop analysis has provided important insights into the underlying physiology of cardiopulmonary resuscitation (CPR). During conventional CPR (C-CPR), ventricular ejection is limited, contributing to poor circulatory effectiveness. In contrast, automated head-up CPR (AHUP-CPR)-which combines active compression-decompression (ACD) CPR, an impedance threshold device (ITD), and controlled head-thorax elevation-generates favorable negative intrathoracic pressure, promoting cerebral venous drainage and increases right heart preload, resulting in enhanced stroke volume, cardiac output, and end-tidal CO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.