Evidence map›Paper›PMID 41648029›Full record

ArticleESMO gastrointestinal oncology2024

Exploring the associations between colorectal polyps and type 2 diabetes mellitus in a colonoscopy clinic population.

J S Kimber, E Symonds, W Uylaki, M Horsnell, P A Drew, E Smith, R R Mikaeel, J E Hardingham, Y Tomita, D Jesudason and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESMO gastrointestinal oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

J S KimberDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
E SymondsBowel Health Service, Flinders Medical Centre, Bedford Park, Australia.
W UylakiDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
M HorsnellDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
P A DrewDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
E SmithDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
R R MikaeelDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
J E HardinghamDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
Y TomitaDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
D JesudasonFaculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.
P J HewettFaculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.
W J BrooksDepartment of Adelaide Medical Solutions, Woodville South, Australia.
J P YoungDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.
T J PriceDepartment of Haematology and Oncology, The Queen Elizabeth Hospital, Woodville South, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: An association has consistently been reported between type 2 diabetes mellitus (T2DM) and colorectal cancer (CRC). CRC develops within premalignant polyps. The aim of this work was to examine the relationship between colorectal polyp subtypes and T2DM across the population, including in low- and non-screening age groups. Material and methods: A cross-sectional study was carried out using an audit of a colonoscopy database and histopathology reports at a tertiary teaching hospital during 2016. Included were consecutive patients undergoing colonoscopy for a diverse range of indications. Univariable and multivariable analyses were carried out to assess the associations between T2DM, age, sex, indications for the procedure and different types of colorectal polyps. Results: Data were extracted from colonoscopies in 1395 patients. Evidence of T2DM was observed in 257 (18%) patients. Any adenoma was present in 109 (42%) patients with T2DM compared with 256 (22%) patients with no evidence of T2DM [odds ratio (OR) 2.5, 95% confidence interval (CI) 1.9-3.4, Conclusions: Adenomas were independently associated with T2DM. Given the consistent association between CRC and T2DM, these data suggest that a diagnosis of T2DM may warrant closer colorectal surveillance.

Indexed as

adenomacolorectal polypsessile serrated lesiontype 2 diabetes mellitus

Identifiers

PMID41648029
PMCPMC12836751

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.