Evidence map›Paper›PMID 41648016›Full record

ArticleFrontiers in microbiology2025

The microevolutionary trajectory of endemic multidrug-resistant tuberculosis strains in Portugal toward increased drug resistance levels and its clinical significance.

Pedro Gomes, Paulo Paixão, Fernando Maltez, Laura Brum, Jody E Phelan, Susana Campino, Taane G Clark, Miguel Viveiros, Isabel Portugal, João Perdigão

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pedro GomesFaculdade de Farmácia, Research Institute for Medicines, Universidade de Lisboa, Lisbon, Portugal.
Paulo PaixãoFaculdade de Farmácia, Research Institute for Medicines, Universidade de Lisboa, Lisbon, Portugal.
Fernando MaltezServiço de Doenças Infecciosas, Hospital Curry Cabral, Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal.
Laura BrumSYNLAB Portugal, Lisbon, Portugal.
Jody E PhelanLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Susana CampinoLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Taane G ClarkLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Miguel ViveirosGlobal Health and Tropical Medicine, GHTM, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, Lisbon, Portugal.
Isabel PortugalFaculdade de Farmácia, Research Institute for Medicines, Universidade de Lisboa, Lisbon, Portugal.
João PerdigãoFaculdade de Farmácia, Research Institute for Medicines, Universidade de Lisboa, Lisbon, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Portugal has one of the highest incidence rates of tuberculosis (TB) in Western Europe and, historically, multidrug-resistant (MDR) cases have been strongly associated with

Indexed as

antimicrobial resistancedrug efficacyendemic transmissionMycobacterium tuberculosispharmacokineticswhole-genome sequencing

Identifiers

PMID41648016
PMCPMC12868246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.