Evidence map›Paper›PMID 41647843›Full record

SynthesisFrontiers in oncology2025

Bibliometric analysis of ovarian cancer immune evasion research from 2015 to 2024.

Xiaodong Wang, Di Xiong, Songli Cui, Bingchen Duan, Yiping Huang, Gouping Ding, Yixuan Tang, Qianqian Wang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaodong WangDepartment of Oncology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
Di XiongDepartment of General Medicine, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
Songli CuiDepartment of Oncology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
Bingchen DuanDepartment of Orthopaedic Surgery, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
Yiping HuangDepartment of Oncology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
Gouping DingDepartment of Oncology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
Yixuan TangDepartment of Oncology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.
Qianqian WangDepartment of Oncology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, Zhuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Ovarian cancer remains lethal and shows limited response to immunotherapy partly due to immune evasion. We mapped global research trends on ovarian cancer immune evasion during 2015-2024. Methods: Web of Science Core Collection and Scopus were searched on 6 Oct 2025 for English articles and reviews published 1 Jan 2015-31 Dec 2024. Records were merged and deduplicated in R (bibliometrix). Productivity, collaboration, keywords, thematic clusters, and burst terms and citations were analyzed using bibliometrix, VOSviewer, and CiteSpace. Results: A total of 496 publications from 202 sources were included, showing rapid growth (annual growth rate ~24.6%) with a marked rise after 2020. The United States and China contributed the most output, whereas international collaboration was limited (~9.7% of authors with multiple-country affiliations). Keyword co-occurrence revealed major themes in immunotherapy, tumor microenvironment remodeling, immune checkpoint regulation, resistance mechanisms, and genetic/epigenetic modulation. Emerging hotspots highlighted tumor-associated macrophages and STAT3-centered signaling as key drivers of immune suppression and therapeutic resistance. Conclusion: Research on ovarian cancer immune evasion is expanding quickly and is shifting toward actionable targets and combination strategies. Strengthening cross-country collaboration and focusing on TME- and STAT3/TAM-directed interventions may accelerate translation and improve immunotherapy outcomes.

Indexed as

bibliometric analysisimmune evasionimmunotherapyovarian cancertumor microenvironment

Identifiers

PMID41647843
PMCPMC12867823

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.