ArticleiGIE : innovation, investigation and insights2025
Resolution of severe ulcerative colitis-associated benign stricture with combined vedolizumab and endoscopic stricturotomy: a case report.
Article in iGIE : innovation, investigation and insights, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ulcerative colitis (UC)-associated strictures, although infrequent, are complex to treat and often prompt surgical resection as a result of concerns about underlying malignancy. However, benign strictures resulting from the inflammation-induced fibrosis represent an important and underaddressed clinical scenario. Although endoscopic stricture therapy is well-established in Crohn's disease-associated strictures, its use in UC has not been described in the literature, to our knowledge. We report a case of a benign colonic stricture in a UC patient after a severe flare who achieved clinical remission with vedolizumab. Endoscopic stricturotomy was performed, resulting in sustained luminal patency over a 2-year follow-up period. Serial biopsies showed no dysplasia. The patient remained in clinical and endoscopic remission. This case suggests that combined medical and endoscopic therapy may promote the resolution of UC-associated benign strictures.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.