Evidence map›Paper›PMID 41647802›Full record

ArticleFrontiers in cardiovascular medicine2025

Case Report: Genomic and clinical insights into MYBPC3-related hypertrophic cardiomyopathy in Ecuadorian patients: implications for sudden cardiac death risk.

Elius Paz-Cruz, Patricia Guevara-Ramírez, Rafael Tamayo-Trujillo, Viviana A Ruiz-Pozo, Santiago Cadena-Ullauri, Rita Ibarra-Castillo, José Luis Laso-Bayas, Leonel Meza-Chico, Alejandro Cabrera-Andrade, Ana Karina Zambrano

Abstract readCase Reports
In one paragraph

Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elius Paz-Cruz *Universidad UTE, Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Quito, Ecuador.
Patricia Guevara-Ramírez *Universidad UTE, Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Quito, Ecuador.
Rafael Tamayo-Trujillo *Universidad UTE, Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Quito, Ecuador.
Viviana A Ruiz-PozoUniversidad UTE, Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Quito, Ecuador.
Santiago Cadena-UllauriUniversidad UTE, Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Quito, Ecuador.
Rita Ibarra-CastilloClinical Cardiac Electrophysiologist, Quito, Ecuador.
José Luis Laso-BayasClinical Cardiac Electrophysiologist, Quito, Ecuador.
Leonel Meza-ChicoUniversidad UTE, Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Quito, Ecuador.
Alejandro Cabrera-AndradeGrupo de Bio-Quimioinformática, Universidad de Las Américas, Quito, Ecuador.
Ana Karina ZambranoUniversidad UTE, Centro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Quito, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and a leading cause of sudden cardiac death (SCD) in young adults and athletes. It exhibits marked clinical variability, which may be influenced by genetic background and environmental factors. Although

Indexed as

cardiovascular diseaseEcuadoriangeneticsgenomicshealthcarehypertrophic cardiomyopathy

Identifiers

PMID41647802
PMCPMC12868290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.