Iron modulation drives biofilm formation and virulence enzyme production in emerging clinical

Shabnam Kumari, Zinnu Rain, Pradyot Prakash, Deepak Kumar, Munesh Kumar Gupta, Ashish Kumar Singh, Ragini Tilak

Abstract read

In one paragraph

Article in Frontiers in fungal biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Computational screening of Alternaria metabolites as potential DPP-4 inhibitors: ADMET, molecular docking, molecular dynamics, and network pharmacology analysis.Molecular diversity · 2026
Article
Virulence determinants, antifungal resistance, and genotype-phenotype associations in Candida bloodstream isolates: a three-year surveillance study from Northern India.Scientific reports · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shabnam Kumari *Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Zinnu Rain *Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Pradyot PrakashDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Deepak KumarDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Munesh Kumar GuptaDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Ashish Kumar SinghDepartment of Biochemistry, Patna University, Patna, India.

Ragini TilakDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The changing epidemiology of candidemia indicates a rise in non-albicans Methods: A total of 216 isolates of Results: Conclusions: Iron differentially influences virulence-associated traits (biofilm-related enzyme activities) and antifungal resistance across these

Indexed as

biofilm-associated infectionsclinical candidemiaechinocandin resistanceemerging fungal pathogensfungal virulenceiron homeostasis

Identifiers

PMID41647768

DOI10.3389/ffunb.2025.1746357

PMCPMC12868186

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.