Evidence map›Paper›PMID 41647741›Full record

ArticleFrontiers in public health2026

Designing a broad-spectrum multi-epitope vaccine against influenza A and

Zhengyu Yang, Yang Li, Lingling Chen, Shulei Jia

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zhengyu YangIntellectual Property Research Institute, Xiamen University, Xiamen, Fujian, China.
Yang LiNational Engineering Research Center for Beijing Biochip Technology (CapitalBio), Beijing, China.
Lingling ChenSchool of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Shulei JiaSchool of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Influenza A and Methods: In this study, a novel dual-target multi-epitope vaccine was developed based on the immunoinformatics method. Based on the consistent sequences, we used the HA and NA proteins of influenza A virus, and the p1, p65, HMW1-3 proteins of Results and Discussion: The designed vaccine included 21 linear B-cell epitopes, 34 CTL epitopes and 19 HTL epitopes from influenza A virus and

Indexed as

Bacterial VaccinesEpitopesInfluenza A virusInfluenza, HumanInfluenza VaccinesMycoplasma pneumoniaePneumonia, MycoplasmaEpitopes, B-LymphocyteEpitopes, T-LymphocyteHumansImmunoinformaticsMolecular Docking SimulationProtein Subunit VaccinesBacterial VaccinesEpitopesEpitopes, B-LymphocyteEpitopes, T-LymphocyteInfluenza VaccinesProtein Subunit Vaccinesdual-target vaccineimmunoinformaticsinfluenza Amulti-epitope vaccineMycoplasma pneumoniae

Identifiers

PMID41647741
PMCPMC12868154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.