Evidence map›Paper›PMID 41647711›Full record

ArticleESMO real world data and digital oncology2025

Development and validation of a clinical prediction model for hospitalization after emergency department admission in patients with cancer.

Z L R Kaplan, D van Klaveren, J G A den Duijn, R J C G Verdonschot, N Wlazlo, J G J V Aerts, J Bromberg, H F Lingsma, J Alsma, M M E M Bos

Abstract read
In one paragraph

Article in ESMO real world data and digital oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Z L R KaplanDepartment of Public Health, Center for Medical Decision Making, Erasmus University Medical Center, Rotterdam, The Netherlands.
D van KlaverenDepartment of Public Health, Center for Medical Decision Making, Erasmus University Medical Center, Rotterdam, The Netherlands.
J G A den DuijnDepartment of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands.
R J C G VerdonschotDepartment of Emergency Department, Erasmus University Medical Center, Rotterdam, The Netherlands.
N WlazloDepartment of Hematology, Erasmus University Medical Center, University Medical Center Cancer Institute, Rotterdam, The Netherlands.
J G J V AertsDepartment of Pulmonary Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
J BrombergDepartment of Neurology, Erasmus University Medical Center, Rotterdam, The Netherlands.
H F LingsmaDepartment of Public Health, Center for Medical Decision Making, Erasmus University Medical Center, Rotterdam, The Netherlands.
J AlsmaDepartment of Internal Medicine-Section Acute Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
M M E M BosDepartment of Medical Oncology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Emergency department (ED) admissions by cancer patients often result in hospitalization and prolonged ED stays, contributing to overcrowding. Early identification of patients at risk of hospitalization could improve ED flow and ensure timely provision of oncological care. This study aimed to develop and validate models to predict hospitalization among cancer patients admitted to the ED. Methods: Adult cancer patients who were admitted to the ED between 1 July 2018 and 30 September 2020 at the Erasmus University Medical Center were included. Data from electronic health records (EHR) were used to develop two logistic regression models: (i) a baseline model including predictors available after ED triage (e.g. patient characteristics, vital parameters) and (ii) an extended model including blood test results. Predictors were selected using the Wald χ Results: Of 7284 ED admissions, 3967 (54%) resulted in hospitalization. The most common cancers requiring hospitalization were lung, hepatopancreatobiliary, and colorectal cancer. The baseline model included age, sex, primary malignancy, symptoms, metastasis, temperature, pain score, diastolic blood pressure, and heart rate. The model showed good calibration (intercept -0.04, slope 0.86) and discriminative ability [C-statistic 0.71, 95% confidence interval (CI) 0.68-0.74]. The extended model showed improved performance (intercept -0.09, slope 0.92; C-statistic 0.75, 95% CI 0.72-0.78). Conclusion: Hospitalization risk of cancer patients admitted to the ED can be predicted using routinely collected EHR data, which could aid in optimizing ED patient flow and ensuring timely provision of oncological services.

Indexed as

care efficiencyclinical prediction modelhospitalizationoncological emergency

Identifiers

PMID41647711
PMCPMC12836634

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.