ArticleiGIE : innovation, investigation and insights2023
High-flow nasal cannula oxygen therapy versus conventional oxygen therapy in prolonged upper GI endoscopy: a randomized controlled trial.
Article in iGIE : innovation, investigation and insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Optimizing Oxygenation during Gastrointestinal Endoscopy: The Rise of HFNC Therapy.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- HFNC Oxygen Therapy vs COT in Prolonged Upper Gastrointestinal Endoscopy Inside the ICU: A Prospective, Randomized, Controlled Clinical Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Supplemental oxygen during upper GI (UGI) endoscopy is considered standard practice, but the optimal modality of oxygen delivery on a prolonged UGI endoscopy procedure is unclear. Given the paucity of data on the impact of a prolonged procedure, we aimed to evaluate the use of high-flow nasal cannula (HFNC) oxygen therapy versus conventional oxygen therapy (COT) in patients undergoing prolonged (>20 minutes) UGI endoscopy. Methods: A prospective randomized controlled trial was conducted at an Australian tertiary hospital. Patients undergoing UGI endoscopy expected to take over 20 minutes were randomized to receive either HFNC oxygen therapy (Optiflow system [Fisher and Paykel Healthcare Ltd, Auckland, New Zealand] at 60 L/min) or COT (standard nasal cannula at 2 L/min). The primary outcome was the incidence of moderate hypoxemia (saturation of peripheral oxygen [SpO Results: Ninety-six patients were included in the intention-to-treat analysis. The incidence of hypoxemia (SpO Conclusions: The use of HFNC oxygen therapy significantly reduced the incidence of hypoxemia among our cohort of patients undergoing prolonged UGI endoscopic procedures. (Clinical trial registration number: ACTRN12620000931976.).
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.