ReviewFundamental research2026
Progress in cellular mechanisms of chronic rhinosinusitis.
Review in Fundamental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Fibroblast Heterogeneity Links Inflammatory Microenvironments to Tissue Remodeling in Chronic Rhinosinusitis.International archives of allergy and immunology · 2026Article
- Effects of Anodal Left DLPFC tDCS on Panic Severity in Panic Disorder Patients With and Without Comorbid Rhinosinusitis and Nasal Septum Deviation.Brain and behavior · 2026Article
- Integration of transcriptomics and machine learning to explore inflammatory characteristics and key oxidative stress-related molecules in nasal polyps.Frontiers in immunology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic rhinosinusitis (CRS) represents one of the most common chronic conditions occurring in the nasal cavity and sinuses, affecting approximately 10% of the global population and imposing a significant socioeconomic burden. The introduction of novel methodologies, notably single-cell sequencing, has unveiled the extensive heterogeneity of structural cells and immune cells, significantly enhanced our understanding of CRS pathogenesis and facilitated the development of more precise diagnostic and therapeutic approaches. Dysfunction of the epithelial barrier, inflammatory memory stored within the epithelium, and the heightened interactions between epithelial cells and immune cells have been implicated in playing pivotal roles in CRS pathogenesis. Emerging evidence highlights the critical role of local immunoglobulin overproduction in CRS. Within ectopic lymphoid tissues (eLTs), a dynamic interplay exists where follicular helper T (Tfh) cells facilitate, while follicular regulatory T (Tfr) cells inhibit, the production of immunoglobulins. Conversely, PD-1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.