Evidence map›Paper›PMID 41647423›Full record

ReviewRSC advances2026

The application of ICG-based photodynamic therapy combined with nanotechnology in tumor treatment.

Hexin Fu, Lu Zhao, Dong Tang

Erratum issuedAbstract readReview
In one paragraph

Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Synthesis and characterization of SPIONs@APTES conjugated with chlorin E6 via carbodiimide for photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Hexin FuNorthern Jiangsu People's Hospital Affiliated to Yangzhou University Yangzhou 225000 China 431245408@qq.com.ORCID https://orcid.org/0009-0006-3797-7183
Lu ZhaoThe Yangzhou Clinical Medical College of Xuzhou Medical University Yangzhou 225001 China.
Dong TangDepartment of General Surgery, Institute of General Surgery, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Northern Jiangsu People's Hospital, The Yangzhou Clinical Medical College of Xuzhou Medical University, The Yangzhou School of Clinical Medicine of Dalian Medical University, The Yangzhou School of Clinical Medicine of Nanjing Medical University, Northern Jiangsu People's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University Yangzhou 225000 China 83392785@qq.com +86-18952783556.ORCID https://orcid.org/0009-0009-6687-3617

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite remarkable progress in tumor therapy, key challenges-including the immunosuppressive "cold" tumor microenvironment and treatment resistance-remain unresolved and severely impede clinical outcomes. Indocyanine Green (ICG)-based Photodynamic Therapy (PDT), a modality that activates the photosensitizer ICG to generate reactive oxygen species (ROS), has emerged as a pivotal strategy to rewire "cold" tumors into immunologically responsive "hot" tumors, laying the foundation for effective combination therapies. However, PDT itself faces inherent limitations (

Identifiers

PMID41647423
PMCPMC12869158

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.