ArticleiGIE : innovation, investigation and insights2025
Hot versus cold snare endoscopic mucosal resection for nonampullary duodenal lesions: consolidating the cold revolution into clinical practice.
Article in iGIE : innovation, investigation and insights, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Cold Resection for Superficial Non-Ampullary Duodenal Epithelial Tumors: Current Evidence and Clinical Perspectives.DEN open · 2027Review
- Safety of cold resection of non-ampullary duodenal polyps: Systematic review and meta-analysis.Endoscopy international open · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Endoscopic mucosal resection (EMR) has increasingly gained acceptance as a minimally invasive intervention for the treatment of duodenal lesions. Despite the overall good results, there can be significant morbidity associated with performing EMR in the duodenum. Data comparing hot snare and cold snare approaches in the duodenum are currently scarce. Our aim was to assess the efficacy and safety of hot snare EMR (H-EMR) versus cold snare EMR (C-EMR) for the resection of nonampullary duodenal lesions. Methods: A retrospective analysis of a prospectively collected database of duodenal lesions treated using EMR at a single tertiary medical center between 2010 and 2023 was performed. Patient demographics, lesion and procedure characteristics, outcomes, and adverse events were analyzed. The primary outcomes studied included complete resection, as assessed by the endoscopist through visual confirmation of complete polyp resection, as well as recurrence and adverse events, including perforation and bleeding. Cost savings were assessed thereafter. Results: Seventy-one cases of nonampullary duodenal lesions resected using the EMR technique were included (46 H-EMR; 25 C-EMR). Fifty-one lesions were resected en bloc (31 H-EMR vs 20 C-EMR), whereas 20 lesions were resected in a piecemeal fashion (15 H-EMR vs 5 C-EMR). Similar demographics and lesion and procedure characteristics were observed in both cohorts. Complete resection was 100%, and no delayed perforations occurred in either cohort. Lesions resected via H-EMR had greater rates of immediate perforation (2.2% vs 0%; Conclusions: Although both cohorts demonstrated excellent complete resection, there was a trend toward lower adverse events and recurrence rates, as well as cost savings, when C-EMR technique was used for nonampullary duodenal lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.