Evidence map›Paper›PMID 41647226›Full record

ArticleArXiv2026

Graph Neural Network Reveals the Local Cortical Morphology of Brain Aging in Normal Cognition and Alzheimer's Disease.

Samuel D Anderson, Nikhil N Chaudhari, Nahian F Chowdhury, Jordan Jomsky, Xiaoyu Rayne Zheng, Andrei Irimia

Abstract readPreprint

In one paragraph

Article in ArXiv, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samuel D AndersonEthel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.

Nikhil N ChaudhariEthel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.

Nahian F ChowdhuryEthel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.

Jordan JomskyEthel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.

Xiaoyu Rayne ZhengDepartment of Materials Science and Engineering, University of California, Berkeley, Berkeley, CA 94720, USA.

Andrei IrimiaEthel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015

$121.0M

MAPPING THE HUMAN CONNECTOME DURING TYPICAL AGINGU01AG052564 · NIA · WASHINGTON UNIVERSITY · PI SALAT, DAVID H, TERPSTRA, MELISSA J · 2016 to 2020

$18.9M

Interpretable machine learning to synergize brain age estimation and neuroimaging geneticsR01AG079957 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Andrei Irimia · 2023 to 2026

$3.2M

NIA NIH HHS R01 AG079957NIA NIH HHS U01 AG024904NIA NIH HHS U01 AG052564

6 · The paper itself

Abstract

Estimating brain age (BA) from T1-weighted magnetic resonance images (MRIs) provides a useful approach to map the anatomic features of brain senescence. Whereas

Indexed as

Graph Neural NetworkLocal Brain AgeMorphometryT1-weighted MRI

Identifiers

PMID41647226

PMCPMC12869401

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.