ReviewClinics in colon and rectal surgery2026
Evidence for Anal Dysplasia Treatment.
Review in Clinics in colon and rectal surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Anal HPV in Kidney Transplant Recipients: A Closer Look at Pathogenesis and Clinical Management.Pathogens (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anal dysplasia, primarily caused by high-risk human papillomavirus (HPV) infection, presents as a precursor to anal cancer (AC), especially among high-risk populations such as human immunodeficiency virus (HIV)-positive individuals. This review evaluates evidence for the treatment of anal intraepithelial neoplasia, focusing on recent advancements in the context of the Anal Cancer/HSIL Outcomes Research Study (ANCHOR) trial which demonstrates that active treatment of high-grade squamous intraepithelial lesions markedly reduced progression to AC. This affirms the value of proactive treatment strategies over passive monitoring. Furthermore, we will discuss various treatment modalities, including topical agents, electrocautery, and HPV vaccination, and their efficacy and limitations. This review underscores the necessity of integrating screening and targeted interventions, particularly for high-risk groups, to reduce AC incidence. Future research should aim to validate these findings across broader demographic groups, refining public health policies and clinical guidelines to include effective screening and treatment protocols.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.