Evidence map›Paper›PMID 41647015›Full record

ArticleFrontiers in medicine2025

Functional quadriceps endurance, dynamic balance, and patient-reported recovery after total knee arthroplasty: a cross-sectional analysis of functional capacity and perceived disability.

Saleh Kardm, Tariq Abdullah Aldugman, Ravi Shankar Reddy, Faisal M Alyazedi

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saleh KardmDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Tariq Abdullah AldugmanDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Ravi Shankar ReddyProgram of Physical Therapy, Department of Medical Rehabilitation Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Faisal M AlyazediDepartment of Physical Therapy, Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Functional quadriceps endurance is a key determinant of physical function after total knee arthroplasty (TKA), yet its relationship with patient-reported outcomes and the potential mediating role of mobility and balance performance remain underexplored. Objectives: To (1) examine the associations between functional quadriceps endurance and patient-reported outcomes (PROMs) after TKA, and (2) test whether dynamic balance and mobility mediate the relationship between endurance and disability. Methods: A cross-sectional study was conducted in 136 individuals (mean age 67.45 ± 6.83 years; 58 males) between 6 and 18 months post-TKA. Participants completed physical performance tests-including the 30-Second Chair Stand, Straight-Leg Raise (SLR), Timed Up and Go (TUG), Four-Square Step Test (FSST), Single-Leg Stance (SLS), and Y-Balance Test-along with PROMs (WOMAC, KOOS, PROMIS Pain Interference, LEFS). Participants were stratified into tertiles based on quadriceps endurance. Analyses included ANOVA, ANCOVA, multiple linear regression, and mediation models using Sobel tests. Results: Higher quadriceps endurance was significantly associated with better PROMs across all domains ( Conclusion: Quadriceps endurance is an independent predictor of pain, function, and daily activity outcomes in TKA patients, with dynamic mobility and balance mediating its effects on disability. These findings support targeting endurance and mobility in postoperative rehabilitation.

Indexed as

mobility limitationpatient-reported outcome measuresphysical endurancequadriceps musclerehabilitationtotal knee arthroplasty

Identifiers

PMID41647015
PMCPMC12868227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.