Evidence map›Paper›PMID 41647005›Full record

ArticleiGIE : innovation, investigation and insights2023

Outcomes of EUS-guided gallbladder drainage in malignant distal biliary obstruction: a systematic review and meta-analysis.

Karim T Osman, Ahmed M Abdelfattah, Maisa E Elbadawi, Tarek Nayfeh, Dhruval Amin, Lina Elkhabiry, Carol Spencer, Prashanth Rau, Neil Marya

Abstract read
In one paragraph

Article in iGIE : innovation, investigation and insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karim T OsmanDivision of Gastroenterology.
Ahmed M AbdelfattahDivision of Gastroenterology.
Maisa E ElbadawiDepartment of Internal Medicine.
Tarek NayfehEvidence-based Practice Center, Mayo Clinic, Rochester, MN.
Dhruval AminDepartment of Internal Medicine, UMass Chan Medical School, Worcester, MA.
Lina ElkhabiryDepartment of Internal Medicine, University of Alexandria, Alexandria, Egypt.
Carol SpencerDepartment of Library Services, Lahey Hospital and Medical Center, Burlington, MA.
Prashanth RauDivision of Gastroenterology.
Neil MaryaDivision of Gastroenterology.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: EUS-guided gallbladder drainage (EUS-GBD) has been described as an alternative palliative treatment for malignant distal biliary obstruction (MDBO). This study assessed the outcomes of EUS-GBD for MDBO. Methods: We conducted a comprehensive literature review of the MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus databases. Formal meta-analysis of pooled outcomes of EUS-GBD for MDBO was performed by using a random effects model. Outcomes of interest were technical success, clinical success, adverse events, and reintervention rates. Pooled estimates were calculated following the restricted maximum likelihood method using a random effects model, and heterogeneity was assessed by using the Results: Fifteen unique articles (a total of 161 patients) were included in the meta-analysis. The pooled technical success rate was 92.10% (95% confidence interval [CI], 84.70-96.09), and the pooled clinical success rate was 81.62% (95% CI, 74.27-97.24). The pooled reintervention rate after achieving clinical success was 13.02% (95% CI, 8.02-20.43), and the pooled adverse event rate was 13.81% (95% CI, 9.19-20.23). The Conclusions: This meta-analysis is the first to evaluate outcomes of EUS-GBD in MDBO. We report high technical and clinical success with relatively low reintervention and adverse event rates. There was no heterogeneity in the data. EUS-GBD is a feasible palliative option for MDBO when conducted at experienced centers.

Identifiers

PMID41647005
PMCPMC12850740

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.