ArticleiGIE : innovation, investigation and insights2023
Comparison of clipping and endoscopic band ligation treatment for the colonic wall: an in vivo animal study.
Article in iGIE : innovation, investigation and insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Although clipping is a simple and widely used treatment for colonic diverticular bleeding, endoscopic band ligation (EBL) has recently been reported to be more effective than clipping in preventing recurrent bleeding. However, the pathologic effects of these treatments on the colonic mucosa remain unclear. This study compares the effects of those treatments on the colonic mucosa using a pig model. Methods: Six clipping procedures and 6 EBL procedures each were performed on the normal colon of the pig, with the clipping and EBL sites separated by approximately 1 cm. The procedure was performed by an expert endoscopist. The pig was killed 10 days after the procedures, and the specimens were compared for pathologic evaluation of necrosis, fibrosis, and disruption of the muscularis mucosae of the colonic mucosa to determine the effects on the colonic mucosa. Results: All bands and clips remained in the procedure site; no perforation was observed at either site. Necrosis was significantly less in the clip group ( Conclusions: The impact on the colonic mucosa is small and localized with clipping but large and extensive with EBL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.