ArticleiGIE : innovation, investigation and insights2023
Randomized controlled trial of procedural sequence for same-day bidirectional endoscopy under monitored anesthesia care (RECoVER Trial).
Article in iGIE : innovation, investigation and insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
RECoVER: Reduction in Sedation: Colonoscopy vs Esophagoduodenoscopy First
Effect of Discontinuing Propofol Anesthesia After Cecal Intubation on Patient's Psychomotor Recovery Following Colonoscopy: A Prospective Two-Arm Parallel Randomized Double-Blind Interventional Controlled Trial
Who cites it
2 citing papers in PubMed.
- Non-operating Room Anesthesia (NORA): A Comprehensive Review of Monitored Anesthesia Care.Cureus · 2024Review
- General anesthesia and/or deep hypnotic state in propofol-based conscious sedation for endoscopy.iGIE : innovation, investigation and insights · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Evidence regarding the ideal endoscopy sequence is inconclusive in patients undergoing same-day bidirectional endoscopy (BDE). Methods: Adults undergoing endoscopy with moderate sedation were randomized to either colonoscopy first (C-E) or EGD first (E-C) under monitored anesthesia care and bispectral index (BIS) monitoring. The primary endpoint was time to recovery from sedation. Secondary endpoints were total amount of sedative, time in deep sedation (defined as BIS <60), patient and endoscopist satisfaction, and adverse events. Patients were contacted the following day for assessment of postdischarge events including delayed recovery and effects on cognitive function and memory. Results: One hundred twenty consecutive patients were enrolled (60 per arm). Baseline characteristics were similar. There was no difference between the C-E and E-C groups in time to recovery (20.2 ± 8.8 minutes vs 17.9 ± 8.8 minutes), dose of propofol (219.9 ± 79.6 mg vs 217.6 ± 79.1 mg), total time spent in deep sedation (7.2 ± 6.6 minutes vs 9.5 ± 7.9 minutes), patient and endoscopist satisfaction, adenoma detection rate (38.3% vs 31.7%, Conclusions: There are no clinically significant differences between procedural sequences in same-day BDE. Decisions regarding the preferred sequence may be individualized, taking into consideration procedural yield, individual risk, and other factors such as the potential for aerosol generation and staff exposure. (Clinical trial registration number: NCT04096339.).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.