Evidence map›Paper›PMID 41646850›Full record

ArticleFrontiers in immunology2026

Non-lethal heat shock unlocks

Xin Zhang, Xiuhong Cai, Shirui Yue, Zhangxuan Chen, Lei Cheng, Shunchang Wang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xin ZhangSchool of Biological Engineering, Huainan Normal University, Huainan, Anhui, China.
Xiuhong CaiSchool of Biological Engineering, Huainan Normal University, Huainan, Anhui, China.
Shirui YueSchool of Biological Engineering, Huainan Normal University, Huainan, Anhui, China.
Zhangxuan ChenSchool of Biological Engineering, Huainan Normal University, Huainan, Anhui, China.
Lei ChengSchool of Biological Engineering, Huainan Normal University, Huainan, Anhui, China.
Shunchang WangSchool of Biological Engineering, Huainan Normal University, Huainan, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oxidative stress and endoplasmic reticulum stress (ERS) are critical for crustaceans' stress responses. Genome-wide identification of superoxide dismutase (SOD) genes in Methods: Five PcSOD genes were identified, with analyses of their structure, motif, chromosomal distribution and phylogeny. Their tissue-specific expression, expression under Results: PcSOD genes showed structural diversity and tissue specificity, with time-dependent expression under bacterial challenge. Heat shock pretreatment regulated their expression timing and intensity. Significant correlations between PcSOD and ERS genes were observed in hemocytes under NLHS + V. Conclusion: These findings suggest a potential coordinated SOD-ERS response in

Indexed as

Disease ResistanceHeat-Shock ResponseSuperoxide DismutaseVibrio InfectionsVibrio parahaemolyticusAnimalsMultigene FamilyPhylogenySuperoxide Dismutasecrust aceanimmunityendoplasmic reticulum stressnon-lethal heat shockProcambarus clarkiiSOD gene family

Identifiers

PMID41646850
PMCPMC12867829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.