Evidence map›Paper›PMID 41646844›Full record

ArticleFrontiers in immunology2026

Clinical impact of first-line chemotherapy combined with immune checkpoint inhibitors for limited-stage small cell lung cancer patients: a real-world propensity score matching study.

Quanman Hu, Chenyi Zhou, Fei Zhao, Xiaoru Song, Yuan Ding, Xiyin Wang, Boying Wu, Huina Wang, Shuaiyin Chen, Bin Jia

Abstract read
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Quanman HuCollege of Public Health, Zhengzhou University, Zhengzhou, China.
Chenyi ZhouFirst Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Fei ZhaoCollege of Public Health, Zhengzhou University, Zhengzhou, China.
Xiaoru SongCollege of Public Health, Zhengzhou University, Zhengzhou, China.
Yuan DingCollege of Public Health, Zhengzhou University, Zhengzhou, China.
Xiyin WangFirst Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Boying WuFirst Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Huina WangCollege of Public Health, Zhengzhou University, Zhengzhou, China.
Shuaiyin ChenCollege of Public Health, Zhengzhou University, Zhengzhou, China.
Bin JiaFirst Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Findings from the ADRIATIC clinical trial revealed that adjuvant treatment with durvalumab following chemoradiotherapy (CRT) in limited-stage small cell lung cancer (LS-SCLC) significantly improved both overall survival (OS) and progression-free survival (PFS). However, the clinical impact remains uncertain in real-world clinical practice. Materials and methods: We gathered data of LS-SCLC patients at the First Affiliated Hospital of Zhengzhou University and conducted propensity score-matched analysis (PSM), Kaplan-Meier (K-M) method and Cox proportional hazards regression. Results: Prior to PSM, survival results demonstrated the mOS of the chemotherapy group was 20.34 months (95% confidence interval ( Conclusion: These results offer reliable references for clinicians when formulating treatment strategies for LS-SCLC patients and also provide support for future clinical trials.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsImmune Checkpoint InhibitorsLung NeoplasmsSmall Cell Lung CarcinomaAgedFemaleHumansMaleMiddle AgedNeoplasm StagingPropensity ScoreTreatment OutcomeImmune Checkpoint InhibitorschemotherapyCox proportional hazardsICIsLS-SCLCprognosticPSM

Identifiers

PMID41646844
PMCPMC12867874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.