Evidence map›Paper›PMID 41646779›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Evaluating Frailty Index Integrity: Insights from an International Network Study.

Robert Cavanaugh, Chelsea Wong, Louisa H Smith, Maytal Bivas-Benita, Pinchas Akiva, Tal El-Hay, Ariela R Orkaby, Chen Yanover, Brianne Olivieri-Mui

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Robert CavanaughMGH Institute of Health Professions, Boston, MA.ORCID 0000-0002-2114-6565
Chelsea WongNortheastern University, Boston, MA.
Louisa H SmithThe Roux Institute, Northeastern University, Portland, ME.ORCID 0000-0001-9029-4644
Maytal Bivas-BenitaKI Research Institute, Kfar Malal, Israel.ORCID 0009-0002-9482-1936
Pinchas AkivaKI Research Institute, Kfar Malal, Israel.ORCID 0000-0003-1535-5536
Tal El-HayKI Research Institute, Kfar Malal, Israel.ORCID 0000-0002-2156-1558
Ariela R OrkabyNew England GRECC (Geriatric Research, Education and Clinical Center), VA Boston Healthcare System, Boston, MA.ORCID 0000-0002-4297-6306
Chen YanoverKI Research Institute, Kfar Malal, Israel.ORCID 0000-0003-3663-4286
Brianne Olivieri-MuiThe Roux Institute, Northeastern University, Portland, ME.ORCID 0000-0001-6739-2019

Funding

Understanding antiretroviral adherence changes from the community to the nursing homeK01AG077972 · NIA · NORTHEASTERN UNIVERSITY · PI Brianne Olivieri-Mui · 2022 to 2026
$616k
NIA NIH HHS K01 AG077972
6 · The paper itself

Abstract

Deficit-accumulation Frailty Indices (FIs) have rapidly been integrated into health systems worldwide to quantify the state of reduced physiologic reserve to recover from a health insult in the aging population. Common data models (CDMs) have further enabled international, interinstitutional applications of FIs. However, the validity of such applications is unknown. We conducted an international network study comparing estimates of frailty from two electronic health record (EHR)-based FIs: United States (US)-based Veterans Affairs FI (VAFI) and United Kingdom (UK)-based electronic FI (eFI) across 5 research and clinical databases. US:

Identifiers

PMID41646779
PMCPMC12870704

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.