ArticlemedRxiv : the preprint server for health sciences2026
Updated Estimates of the Global, Regional and National Burden, and Etiology of Diarrheal Diseases Transmissible via Food: A Systematic Review and Meta-Analytical Modelling Study for the World Health Organization.
Josh M Colston, Brecht Devleesschauwer, Thomas Flynn, Francesca Schiaffino, Adhvikaa Ambikapathi Revathi, Nasif Hossain, Yen Ting Chen, Danielle Meister, Ava Bagherian, Olivia Binggeli and 12 more
Abstract readPreprint
In one paragraphArticle in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
22 authors.
Josh M ColstonDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0003-4567-5813 Thomas FlynnDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-9262-9601 Francesca SchiaffinoDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0002-5796-5116 Adhvikaa Ambikapathi RevathiSchool of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID 0009-0003-9474-2338 Yen Ting ChenBayhealth, Delaware, USA.
Danielle MeisterCollege of Arts and Sciences, University of Virginia, Charlottesville, Virginia, USA.
Ava BagherianCollege of Arts and Sciences, University of Virginia, Charlottesville, Virginia, USA.
Olivia BinggeliCollege of Arts and Sciences, University of Virginia, Charlottesville, Virginia, USA.
Emily ZhengCollege of Arts and Sciences, University of Virginia, Charlottesville, Virginia, USA.
Nhiya DavidCollege of Arts and Sciences, University of Virginia, Charlottesville, Virginia, USA.
Elaine Scallan WalterColorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0003-1766-0307 Martyn D KirkNational Centre for Epidemiology and Population Health, Australian National University, Australia.ORCID 0000-0001-5432-5984 Arie H HavelaarEmerging Pathogens Institute, Global Food Systems Institute, Department of Animal Sciences, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-6456-5460 Shannon E MajowiczSchool of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.ORCID 0000-0002-0006-8369 Margaret N KosekDivision of Infectious Diseases and International Health, School of Medicine, University of Virginia, Charlottesville, Virginia, USA.ORCID 0000-0001-6340-4852 Funding
INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3MGenomic Epidemiology of Campylobacter in Poultry to Enable the Effective Control of Human Campylobacteriosis in a Middle Income CountryK43TW012298 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI Francesca Schiaffino · 2022 to 2026
$811kThe Planetary Child Health Observatory: an interdisciplinary research initiative and web-based dashboard for mapping enteric infectious diseases and their risk factors and interventions in LMICsK01AI168493 · NIAID · UNIVERSITY OF VIRGINIA · PI Josh M Colston · 2023 to 2026
$519kFIC NIH HHS K43 TW012298NIAID NIH HHS K01 AI168493NIAID NIH HHS T32 AI007046
6 · The paper itselfAbstract
Diarrheal disease is caused by diverse species of viruses, bacteria and protozo that are transmitted from different sources, including from contaminated food. Sustaining progress in reducing diarrheal illnesses and deaths, including vaccines and food safety measures, may require interventions targeting specific pathogens. In 2015, the WHO's published etiology-specific estimates by their Foodborne Disease Burden Epidemiology Reference Group (FERG) of the incidence and mortality of diarrheal diseases caused by 11 pathogens at global and regional scales in 2010. Since then, much new evidence has been published about the epidemiology of enteropathogens. This study aims to update estimates to the year 2021 with the addition of three pathogens (Rotavirus,
Indexed as
Bacterial infectionsDiarrheal DiseaseEnteric PathogensGlobal HealthProtozoal infectionsViral infections
Identifiers
PMID41646776
PMCPMC12870551
What OpenQuestion holds
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LicenceCC BY-NC-ND
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