Evidence map›Paper›PMID 41646738›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Is

Marzieh Khani, Sheila N Yeboah, Catalina Cerquera-Cleves, Alexandra Kedmi, Bernabe I Bustos, Spencer M Grant, Suleyman Can Akerman, Fulya Akçimen, Paul Suhwan Lee, Paula Reyes-Pérez and 19 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

Marzieh KhaniCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0003-0649-6644
Sheila N YeboahCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0009-0005-7546-1236
Catalina Cerquera-ClevesDepartment of Neurosciences, Neurology Unit, Hospital Universitario San Ignacio, Bogotá, Colombia.ORCID 0000-0002-3874-0261
Alexandra KedmiCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.
Bernabe I BustosKen and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0003-2679-9503
Spencer M GrantCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0002-7278-0347
Suleyman Can AkermanBrain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.ORCID 0000-0001-8424-1917
Fulya AkçimenMolecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, and National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0931-5247
Paul Suhwan LeeCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0003-2658-4641
Paula Reyes-PérezLaboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Blvd. 3001, Campus UNAM 3001, Juriquilla, QRO, 76230, México.ORCID 0000-0001-8062-7441
Lara M LangeMolecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, and National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-7162-9821
Hampton LeonardCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0003-2390-8110
Mathew J KoretskyCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0003-4341-3991
Mary B MakariousCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0002-7978-1051
Zachary SchneiderCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0009-0001-3738-5368
Caroline JonsonCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0001-7049-6281
Pin-Shiuan ChenDepartment of Neurology, National Taiwan University Hospital Bei-Hu branch, Taipei, Taiwan.ORCID 0000-0003-3992-1942
Yi Wen TayDepartment of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-9319-0768
Jeffrey D RothsteinBrain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.ORCID 0000-0003-2001-8470
Chin-Hsien LinDepartment of Neurology, National Taiwan University Hospital, Taipei, Taiwan.ORCID 0000-0001-8566-7573
Shen-Yang LimDivision of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.ORCID 0000-0002-6942-2522
Christine KleinInstitute of Neurogenetics, University of Lübeck, Lübeck, Germany.ORCID 0000-0003-2102-3431
Kalpana MerchantKen and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0003-1118-9403
Niccolò E MencacciKen and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0003-3383-9665
Dimitri KraincKen and Ruth Davee Department of Neurology and Simpson Querrey Center for Neurogenetics, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.ORCID 0000-0002-4716-1886
Mark R CooksonCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0002-1058-3831
Global Parkinson’s Genetics Program (GP2)
Andrew SingletonGlobal Parkinson's Genetics Program, USA.ORCID 0000-0001-5606-700X
Sara Bandres-CigaCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892 USA.ORCID 0000-0003-0056-1361

Funding

Technology to Empower Changes in Health (TECH) Network Participant Technologies CenterU24OD023176 · OD · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2016 to 2022
$204.7M
Precision Medicine Initiative Cohort Program BiobankU24OD023121 · OD · MAYO CLINIC ROCHESTER · PI CEKANOVA, MARIA, CICEK, MINE · 2016 to 2024
$185.5M
Enhancing All of Us Data Resources for Nutrition Precision Health: the All of Us Data and Research CenterU2COD023196 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GLAZER, DAVID, HARRIS, PAUL A. · 2016 to 2022
$143.7M
Adaptive Platform for Personalized EngagementU24OD023163 · OD · VIGNET, INC. · PI JAIN, PRADUMAN · 2017 to 2020
$102.6M
University of Arizona-Banner Health All of Us Research Program OT2OD026549 · OD · UNIVERSITY OF ARIZONA · PI MORENO, FRANCISCO A, REIMAN, ERIC MICHAEL · 2018 to 2023
$78.9M
California Precision Medicine Research Program ConsortiumOT2OD026552 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANTON-CULVER, HODA A, OHNO-MACHADO, LUCILA · 2018 to 2023
$73.4M
All of Us PennsylvaniaOT2OD026554 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E, VISWESWARAN, SHYAM · 2018 to 2023
$72.1M
New York City Consortium for Precision MedicineOT2OD026556 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BIER, LOUISE E, GHARAVI, ALI G · 2018 to 2023
$67.3M
SouthEast Enrollment Center (SEEC) OT2OD026551 · OD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, COLON, VIVIAN · 2018 to 2023
$62.8M
Southern All of Us NetworkOT2OD026548 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N., KORF, BRUCE R · 2018 to 2023
$60.5M
Illinois Precision Medicine Consortium OT2OD026557 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI AHSAN, HABIBUL, ARGOS, MARIA · 2018 to 2023
$60.5M
The New England Precision Medicine Consortium of the All of Us Research ProgramOT2OD026553 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CLARK, CHERYL RENEE, KARLSON, ELIZABETH W · 2018 to 2023
$58.8M
Intramural NIH HHS ZIA AG000949NIA NIH HHS U24 AG041689NIH HHS OT2 OD023205NIH HHS OT2 OD023206NIH HHS OT2 OD025276NIH HHS OT2 OD025277NIH HHS OT2 OD025315NIH HHS OT2 OD025337NIH HHS OT2 OD026548NIH HHS OT2 OD026549NIH HHS OT2 OD026550NIH HHS OT2 OD026551NIH HHS OT2 OD026552NIH HHS OT2 OD026553NIH HHS OT2 OD026554NIH HHS OT2 OD026555NIH HHS OT2 OD026556NIH HHS OT2 OD026557NIH HHS U24 OD023121NIH HHS U24 OD023163NIH HHS U24 OD023176NIH HHS U2C OD023196NINDS NIH HHS U01 NS082133NINDS NIH HHS U01 NS082134NINDS NIH HHS U01 NS082137NINDS NIH HHS U01 NS082148NINDS NIH HHS U01 NS082151NINDS NIH HHS U01 NS082157
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseburden analysisdementiadisease-causing variantsfamily-based analysisgenetic risk factorsGWASParkinson’s diseaseSORL1whole-genome sequencing

Identifiers

PMID41646738
PMCPMC12870714

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.