ArticleFrontiers in surgery2025
What is the role of pre-operative sperm DNA fragmentation index in microsurgical varicocelectomy success?
Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Is Varicocele Truly Unilateral? Contralateral Involvement and Bilateral Testicular Effects in Male Infertility: A Narrative Review.Journal of personalized medicine · 2026Review
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Authors and funding
3 authors.
Funding
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Abstract
Objective: This prospective study aimed to examine the effect of pre-operative sperm DFI on varicocelectomy success. Material and methods: A total of 51 infertile men with unilateral clinical VC who met the inclusion criteria and underwent microsurgical varicocelectomy were enrolled. As described in previous studies, in our study, more than 50% increase in total motile sperm count (TMSC) in post-operative semen analysis was defined as a significant improvement. However, at least a 100% increase was required for patients with a TMSC <5 million in the definition of recovery. The patients were separated as two groups as benefiting from the treatment and not. Results: Among the 31 patients who completed the 3-month follow-up, significant improvements were observed in sperm concentration, total sperm count, TMSC, abnormal sperm morphology, and DFI ( Conclusions: Our study showed that high sperm DFI (≥28.71%) may be a useful pre-operative predictive tool in identifying men who benefit most from varicocelectomy in infertile patients with VC.
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