ArticleCureus2026
Clinical Presentation and Management of Swyer Syndrome: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A pure 46, XY gonadal dysgenesis, or Swyer syndrome, is an extremely rare condition causing primary amenorrhea. It is distinguished by the existence of a female phenotype with a 46, XY karyotype. Reports of new cases are essential to improve early diagnosis and management. We present a case of a 16-year-old Moroccan girl with pubertal delay. The patient exhibited a female, partially developed morphology with Tanner stage 2 secondary sexual characteristics, and a hormonal profile consistent with hypergonadotropic hypogonadism. Morphological evaluation revealed the presence of a uterus and vaginal cavity without visualization of the ovaries. Chromosomal analysis confirmed the diagnosis of Swyer syndrome. A laparoscopic operation revealed bilateral striated gonads, which had to be removed because of the risk of malignancy. Following the operation, estrogen-only pubertal induction was initiated, followed later by progesterone. The case highlights the importance of considering Swyer syndrome in adolescent girls presenting with primary amenorrhea and delayed puberty. Our report features atypical characteristics, including partially spontaneous pubertal development and pronounced short stature, which may delay both diagnosis and treatment. Nevertheless, earlier diagnosis and comprehensive management, including early gonadectomy, hormone replacement therapy, and psychological support, remain essential for optimal outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.