ArticleCureus2026
Serum Uric Acid Levels and Renal Function in Untreated Hypertensive Patients.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Uric Acid and Chronic Kidney Disease.Kidney medicine · 2026Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim Serum uric acid is considered to be a risk factor contributing to the progression of cardiovascular disease. In this cross-sectional study that used existing data, we evaluated possible correlations between serum uric acid levels and renal function and the hypothesis that elevated serum uric acid levels may be associated with worse renal function in untreated patients with arterial hypertension. Patients and methods The study involved 446 hypertensive patients (226 men, 220 women) of 52.7 ± 12.6 years of age who visited our Outpatient Hypertension Clinic and did not receive any antihypertensive therapy. Results Patient separation into three groups according to serum uric acid (SUA) levels (SUA: <6, 6-8, >8 mg/dl) showed that patients with lower serum uric acid levels had lower creatinine levels and higher estimated glomerular filtration rate (eGFR), as calculated by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation, and vice versa. A statistically significant correlation was observed between serum uric acid levels and either serum creatinine levels (r=0.54, p<0.001) or eGFR (r=-0.19, p<0.01). Conclusions Untreated hypertensive subjects with higher serum uric acid levels exhibit reduced renal function compared with hypertensive individuals with lower serum uric acid levels.
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Registered trials
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