Evidence map›Paper›PMID 41646416›Full record

ArticleResearch square2026

Clinical characteristics of

Mitch M Matoga, Jane S Chen, Sarah E Rutstein, Gomezgani Lukhanda, Farhang Aghakanian, Jonathan J Juliano, Jonathan B Parr, Magnus Unemo, Irving F Hoffman, Arlene C Sena

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mitch M MatogaUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.ORCID https://orcid.org/0000-0002-6542-8193
Jane S ChenInstitute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, USA.
Sarah E RutsteinDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Institute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, USA.
Gomezgani LukhandaUniversity of North Carolina Project-Malawi, Lilongwe, Malawi.
Farhang AghakanianInstitute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, USA.
Jonathan J JulianoDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Institute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, USA.
Jonathan B ParrDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Institute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, USA.
Magnus UnemoWHO Collaborating Centre for Gonorrhoea and Other STIs, Örebro University, Örebro, Sweden; Institute for Global Health, University College London (UCL), London UK.
Irving F HoffmanDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Institute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, USA.
Arlene C SenaDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Institute for Global Health and Infectious Diseases, University of North Carolina, Chapel Hill, USA.

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Prevalence of syphilis and other sexually transmitted infections in men and transgender women who have sex with men in Cali, ColombiaU19AI144177 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RADOLF, JUSTIN D · 2019 to 2023
$11.2M
Gates Foundation INV-036560NIAID NIH HHS P30 AI050410NIAID NIH HHS U19 AI144177
6 · The paper itself

Abstract

Background: Chancroid, a sexually transmitted infection (STI) caused by Methods: We combined data from two recent studies conducted in Malawi (2019-2022, 2021) that screened and enrolled patients ≥ 18 years of age presenting to a STI clinic with GUD. Polymerase chain reaction (PCR) was conducted for Results: Among 618 participants with GUD, 137 (22%) tested positive for Conclusions: This review confirmed the high prevalence and persistence of chancroid in Malawi. However, additional investigations are needed to further characterize the epidemiology of chancroid and determine the reasons for its persistence in Malawi.

Indexed as

chancroidclinical and sexual characteristicsepidemiologygenital ulcer disease (GUD)Haemophilus ducreyi

Identifiers

PMID41646416
PMCPMC12869566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.