Evidence map›Paper›PMID 41646377›Full record

ArticleResearch square2026

A Physics-Informed Neural Network for

Leshan Sun, Kristina Bjegovic, Lucia Rodriguez-Gonzalez, Yifei Xu, Yuchen Yan, Gilberto Gonzalez, Lucy Whitmore, Luke Connell, Yankun Lang, Prabodh Pandey and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leshan SunThe Department of Biomedical Engineering, University of California, Irvine, Irvine, United States.
Kristina BjegovicThe Department of Biomedical Engineering, University of California, Irvine, Irvine, United States.
Lucia Rodriguez-GonzalezThe Department of Biomedical Engineering, University of California, Irvine, Irvine, United States.
Yifei XuThe Department of Biomedical Engineering, University of California, Irvine, Irvine, United States.
Yuchen YanThe Department of Biomedical Engineering, University of California, Irvine, Irvine, United States.
Gilberto GonzalezDepartment of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma city, OK, United States.
Lucy WhitmoreDepartment of Radiation Physics Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Luke ConnellUTHealth Houston Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Yankun LangDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, United States.
Prabodh PandeyThe Department of Radiological Sciences, University of California, Irvine, Irvine, United States.
Lei RenDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, United States.
Emil Sch LerDepartment of Radiation Physics Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Yong ChenDepartment of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma city, OK, United States.
Shawn XiangThe Department of Biomedical Engineering, University of California, Irvine, Irvine, United States.

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
Academic-Industry Partnership for the Translation of a 4D in vivo Dosimetry Approach for Radiation TherapyR37CA240806 · NCI · UNIVERSITY OF OKLAHOMA · PI CHEN, YONG, IVANOV, VASSILI · 2019 to 2025
$2.9M
3D In vivo dosimetry for FLASH proton therapyU01CA288351 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Yong Chen, Lei Ren · 2024 to 2026
$1.8M
Quantitative in vivo dosimetry for radiotherapy using model-based X-ray-induced acoustic computed tomographyR50CA283816 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Prabodh Kumar Pandey · 2024 to 2026
$317k
NCI NIH HHS P30 CA062203NCI NIH HHS R37 CA240806NCI NIH HHS R50 CA283816NCI NIH HHS U01 CA288351
6 · The paper itself

Abstract

Accurate dosimetry is critical for safe and effective radiotherapy, yet no clinical method currently measures dose directly within the patient

Indexed as

In Vivo DosimetryPhysics-informed Neural NetworkQuantitative Radiacoustic ImagingRadiotherapy

Identifiers

PMID41646377
PMCPMC12869649

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.