ArticleResearch square2026
Suppression of transgenerational lipid provisioning inhibits desiccation resistance, but not diapause, in the vector mosquito, Aedes albopictus.
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Transgenerational signaling allows many organisms to anticipate seasonal variation. Diapause, a hormonally-programmed period of developmental arrest, is a widespread anticipatory seasonal response that is often mediated by transgenerational signaling. Despite the well-established adaptive significance of diapause, the molecular and physiological basis of transgenerational diapause signaling remains largely unresolved. Since lipid accumulation is a hallmark of diapause preparation, we hypothesized that increased lipid provisioning and accumulation mediate transgenerational diapause signaling. To test this hypothesis, we suppressed transcripts of two lipid metabolism genes using RNA-interference in the maternal generation of the vector mosquito,
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