Evidence map›Paper›PMID 41646287›Full record

ArticleResearch square2026

Research Support Networks for Substance Use Translational Research: A Qualitative Evaluation of the HEAL Data to Action (HD2A) Program.

Lawrence A Palinkas, C Hendricks Brown, Heather J Gotham, Emma E McGinty, Ethan Lai, Meredith C B Adams, Mark P McGovern

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lawrence A PalinkasUniversity of California San Diego.
C Hendricks BrownNorthwestern University.
Heather J GothamStanford University School of Medicine.
Emma E McGintyWeill Cornell College of Medicine.
Ethan LaiUniversity of California San Diego.
Meredith C B AdamsWake Forest University School of Medicine.
Mark P McGovernStanford University School of Medicine.

Funding

Use of topic modeling and stakeholderengagement to map determinants of implementation disparities in addiction and pain researchU2CDA057717 · NIDA · STANFORD UNIVERSITY · PI C. HENDRICKS BROWN · 2022 to 2026
$19.1M
NIDA NIH HHS U2C DA057717
6 · The paper itself

Abstract

Background: NIH-funded research has been increasingly conducted in collaborative consortia of investigators with the support of coordinating centers. However, the extent to which such initiatives help to accomplish NIH goals and objectives with respect to the translation of research to practice remains unclear. We evaluated the progress being made by individual Helping to End Addiction Long-term Methods: A qualitative observational study conducted as part of a mixed method formative evaluation. Data were collected from semi-structured group interviews and interview transcripts were analyzed using thematic content analysis. Principal investigators and key personnel (n = 33) for each of the 10 NIDA-funded HD2A projects annually beginning in March 2023. Members of the three support centers (n = 8) were also interviewed in January 2025. Results: Three overall themes with several subthemes were identified: 1) accomplishments and challenges of individual projects; 2) HD2A Support Center activities; and 3) overall assessment of HD2A participation. All projects made significant progress and obtained needed support from the three research support centers. Project implementation activities were strengthened overall. Grantees that received supplemental funding for rapid data infrastructure projects benefitted from that funding. Interactions with other HD2A projects was limited but viewed favorably by all grantees. All projects were funded by a phasic NIH grant mechanism. Transitioning from the R61 planning phase to the R33 study phase was a minor challenge for some projects but successfully addressed with the assistance of NIDA personnel. Efforts to harmonize data across the projects have encountered barriers and will require additional support and guidance. Conclusions: Initiatives to bring together diverse projects having a common aim or theme create opportunities for accessing needed support for implementation and collaboration across projects as intended. Nevertheless, greater engagement between those providing technical assistance and those receiving it and stipulating common data elements should occur prior to submission of applications for funding.

Indexed as

health services researchimplementationopioid-related disorderspain managementresearch supporttranslational research

Identifiers

PMID41646287
PMCPMC12869576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.