ArticlePalliative care and social practice2025
Parenteral morphine and oxycodone mixtures administered in specialised palliative and hospice care units: A retrospective medical record review.
Article in Palliative care and social practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Continuous subcutaneous infusions combining several drugs are routinely used in palliative care, particularly for severe pain management. Parenteral administration routes, however, have been found to be prone to errors. According to previous studies, standardising the compositions of parenteral mixtures can improve medication safety. Objectives: To evaluate the potential for standardisation of parenteral drug mixtures used in palliative and hospice care by identifying the most commonly administered compositions of mixtures containing morphine or oxycodone. Design: A retrospective medical record review of parenteral drug mixture administrations containing morphine or oxycodone. Methods: Drug administration records of 120 deceased patients treated in two inpatient units and in the At-home hospital providing palliative and hospice care in the City of Helsinki, Finland, were collected. The data were analysed with descriptive statistics. Results: The patients ( Conclusion: Although palliative and hospice care patients need individualised medications, standardisation might be possible for the morphine-based drug mixtures and for the mixtures containing midazolam and haloperidol admixed with morphine or oxycodone.
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