Evidence map›Paper›PMID 41646220›Full record

ArticleESMO real world data and digital oncology2025

Cancer prevalence and care disparities among individuals with intellectual disabilities: a cross-sectional pan-cancer analysis.

T Sappok, M-L Rosenbusch, R Hering, M Schulz, C Kowalski, N T Sibert, T Seufferlein, A W Berger

Abstract read
In one paragraph

Article in ESMO real world data and digital oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

T SappokMedical School and University Medical Center OWL, Bielefeld University, University Clinic for People with Neurodevelopmental Disorders, Mara Hospital, Bielefeld, Germany.
M-L RosenbuschCentral Research Institute of Ambulatory Health Care in Germany, Berlin, Germany.
R HeringCentral Research Institute of Ambulatory Health Care in Germany, Berlin, Germany.
M SchulzCentral Research Institute of Ambulatory Health Care in Germany, Berlin, Germany.
C KowalskiDepartment of Health Services Research, German Cancer Society, Berlin, Germany.
N T SibertDepartment of Health Services Research, German Cancer Society, Berlin, Germany.
T SeufferleinUlm University Hospital, Department of Internal Medicine I, Ulm, Germany.
A W BergerUlm University Hospital, Department of Internal Medicine I, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: People with intellectual disability (ID) face considerable health disparities, with cancer being among the most frequent causes of premature death. A systematic analysis of the health care situation is necessary to further strengthen treatment and support for this highly vulnerable population. Patients and methods: In this cross-sectional study we analysed nationwide German outpatient health insurance data of 437 802 people with ID, which were compared to an age-, sex-, and district code-matched sample of people without ID. Results: Overall, people with ID (4.2% with cancer) showed lower odds ratios for a cancer diagnosis compared with the matched cohort without ID (5.1% with cancer) [C00-C97: odds ratio 0.83; 95% confidence interval 0.82-0.84; Conclusions: Difficulties in accessing the health care system and lower cancer screening rates may contribute to fewer cancer diagnoses. Our findings highlight specific cancer types-notably brain cancer, leukaemia, testicular and ovarian tumours-that show higher prevalence in individuals with ID compared with individuals without ID. These data underscore the increased vulnerability of the ID population to these particular malignancies, guiding future research, patient care, and screening efforts.

Indexed as

cancerhealth disparitiesintellectual disabilityprevalencescreening programmes

Identifiers

PMID41646220
PMCPMC12836748

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.