Evidence map›Paper›PMID 41646162›Full record

ArticleClinical case reports2026

Incidental Diagnosis of Erdheim-Chester Disease in a 42-Year-Old Man With Persistent Elevated ESR and Peri-Ocular Xanthomas: A Case Report.

Mohammad Rahimi, Alireza Ghanadan, Nooshin Shirzad, Mehrnaz Doostmohammadi, Mahboobeh Hemmatabadi

Abstract read
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohammad RahimiDepartment of Endocrinology, Endocrinology and Metabolism Research Center, Vali-Asr Hospital, Imam Khomeini Complex Hospital Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0009-0003-0735-4207
Alireza GhanadanDepartment of Pathology, Cancer Institute Imam Khomeini Complex Hospital Tehran Iran.
Nooshin ShirzadDepartment of Endocrinology, Endocrinology and Metabolism Research Center, Vali-Asr Hospital, Imam Khomeini Complex Hospital Tehran University of Medical Sciences Tehran Iran.
Mehrnaz DoostmohammadiDepartment of Pathology, Cancer Institute Imam Khomeini Complex Hospital Tehran Iran.
Mahboobeh HemmatabadiDepartment of Endocrinology, Endocrinology and Metabolism Research Center, Vali-Asr Hospital, Imam Khomeini Complex Hospital Tehran University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-9305-6657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by multisystem involvement and frequent diagnostic delay due to nonspecific clinical manifestations. We report a 42-year-old asymptomatic man with persistently elevated erythrocyte sedimentation rate (ESR) detected during routine laboratory evaluation. Physical examination revealed bilateral peri-ocular xanthomas. Multimodal imaging demonstrated bilateral perirenal soft-tissue infiltration with a characteristic "hairy kidney" appearance on computed tomography, symmetric skeletal involvement on bone scintigraphy, and metabolically active lesions on

Indexed as

diagnostic imagingErdheim–Chester diseasenon‐Langerhans cell histiocytosisPET/CTXanthomatosis

Identifiers

PMID41646162
PMCPMC12868932

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.