Evidence map›Paper›PMID 41646139›Full record

ArticleiGIE : innovation, investigation and insights2024

Outcomes of phosphorus-32 microparticle intratumoral implantation added to chemotherapy in patients with metastatic pancreatic adenocarcinoma.

Amanda Huoy Wen Lim, Nimit Singhal, Dylan Bartholomeusz, Joshua Zobel, Jeevinesh Naidu, William Hsieh, Benjamin Crouch, Harpreet Wasan, Daniel Croagh, Adnan Nagrial and 4 more

Abstract read
In one paragraph

Article in iGIE : innovation, investigation and insights, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Amanda Huoy Wen LimGastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Nimit SinghalOncology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Dylan BartholomeuszGastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Joshua ZobelGastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Jeevinesh NaiduGastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
William HsiehDepartment of Nuclear Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Benjamin CrouchDepartment of Nuclear Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Harpreet WasanOncology, Imperial College Healthcare NHS Trust, London, United Kingdom.
Daniel CroaghUpper Gastrointestinal and Hepatobiliary Surgery, Monash Medical Center, Clayton, Victoria, Australia.
Adnan NagrialOncology, Westmead Hospital, Westmead, New South Wales, Australia.
Morteza AghmeshehOncology, Wollongong Hospital, Wollongong, New South Wales, Australia.
Edmund TseGastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Christopher K RaynerGastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Nam Quoc NguyenGastroenterology and Hepatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Metastatic pancreatic ductal adenocarcinoma (mPDAC) has a 5-year survival rate of 3%. In nonmetastatic, locally advanced pancreatic cancer, the addition to chemotherapy of EUS-guided intratumoral phosphorus-32 ( Methods: Patients with mPDAC treated with chemotherapy and intratumoral Results: Fourteen patients were treated (7 female subjects; median age, 64.5 years; Eastern Cooperative Oncology Group performance status scores 0/1/2, 21.4%/57.1%/21.4%). The median baseline primary tumor longest diameter was 40.5 mm. Patients had a median of 3 metastases (interquartile range, 2.25 to 5) and received either 5-fluorouracil, leucovorin, irinotecan, and oxaliplatin (n = 4) or gemcitabine/nab-paclitaxel (n = 10). Conclusions: This first multicenter analysis of combined chemotherapy and EUS-guided

Identifiers

PMID41646139
PMCPMC12850732

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.