Evidence map›Paper›PMID 41646127›Full record

ArticlePsychology of consciousness (Washington, D.C.)2025

A Randomized Controlled Trial of Hypnosis to Manage Musculoskeletal Pain in Breast Cancer Survivors Taking Aromatase Inhibitors.

Guy H Montgomery, Julie B Schnur, Amy Tiersten, Kelley Benck, Joel Erblich

Abstract read
In one paragraph

Article in Psychology of consciousness (Washington, D.C.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hypnosis at the Crossroads: A Primer of the Past and Visions for the Future.The International journal of clinical and experimental hypnosis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Guy H MontgomeryCenter for Behavioral Oncology, Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY.
Julie B SchnurCenter for Behavioral Oncology, Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY.
Amy TierstenDepartment of Medicine, Hematology, and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY.
Kelley BenckUniversity of Miami Miller School of Medicine, Miami, FL.
Joel ErblichCenter for Behavioral Oncology, Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, NY.

Funding

Enhancing the public health benefits of mammography screening by informing women of both breast cancer and breast arterial calcification results: A randomized trial to promote cardiovascular healthR01CA251754 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MONTGOMERY, GUY H · 2021 to 2025
$3.4M
Hypnosis to reduce aromatase inhibitor (AI)-associated musculoskeletal pain and to improve AI adherence: An RCT to explore clinical efficacy and cost effectsR01AT008762 · NCCIH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MONTGOMERY, GUY H · 2015 to 2019
$2.6M
NCCIH NIH HHS R01 AT008762NCI NIH HHS R01 CA251754
6 · The paper itself

Abstract

The aim of this study was to test the efficacy of a three-session hypnosis intervention to manage musculoskeletal pain (MSP) in breast cancer survivors taking aromatase inhibitors (AIs). We hypothesized that patients in the hypnosis group would have lower levels of pain than patients in an attention control group. A secondary outcome was to examine intervention effects on AI adherence. Patients (n=154) were randomly assigned to a hypnosis (n=76; mean) or to an attention control (n=78; mean) group. MSP was measured at five time points (baseline, 3, 6, 9, and 12 months) using the BPI-SF (severity, primary outcome), the BPI-SF (interference), the WOMAC, the AUSCAN and the BCPT-MS. AI adherence was measured using eCAPs and self-report (MARS). The hypnosis group had significantly lower BPI-SF severity (p< 0.01) and interference (p< 0.03) scores across assessment points. The AUSCAN [total (p< 0.01), pain (p< 0.01), stiffness (p< 0.04), and function (p< 0.04)] and the BCPT-MS (p< 0.001) scales showed similar results in favor of hypnosis. WOMAC pain (p< 0.02) and stiffness (p< 0.01) subscales were also in favor of the hypnosis group, but differences on WOMAC function were non-significant (p >0.11). AI adherence scores did not differ between the groups (eCAP p >0.80, MARS ps >0.18). Results support hypnosis as efficacious for controlling MSP in breast cancer survivors taking AIs. Hypnosis is brief, has no specific side-effects, can be taught to patients to use on their own, and its beneficial effects persist long after the last intervention session.

Indexed as

AdherenceBreast CancerHypnosisPain management

Identifiers

PMID41646127
PMCPMC12872219

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.