ArticleIntestinal Failure (New York, N.Y.)
Necrotizing enterocolitis in a patient with Microvillous Inclusion Disease: A case report.
Article in Intestinal Failure (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Microvillous Inclusion Disease (MVID) is a rare congenital disorder causing severe diarrhea from early infancy, typically requiring long-term parenteral nutrition (PN). It results from MYO5B gene mutations, disrupting brush border protein trafficking. Necrotizing enterocolitis (NEC) is not typically linked to MVID, with only two cases reported so far. Case report: A 5-month-old male with MVID developed worsening diarrhea after switching from breast milk to polymeric formula, leading to dehydration and metabolic acidosis. Amino acid-based formula did not improve his condition. Imaging confirmed NEC, showing pneumatosis intestinalis and gas in the portal system. Conservative treatment stabilized his condition, and stool output improved after switching to donated breast milk. Conclusion: This case underscores the potential risk of NEC in MVID patients, emphasizing the need for careful management of enteral feeding. Clinicians should maintain a high index of suspicion for NEC due to these patients' susceptibility to hypoperfusion and mucosal integrity issues.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.