Evidence map›Paper›PMID 41646109›Full record

ReviewIntestinal Failure (New York, N.Y.)

Pharmacologic challenges in pediatric intestinal failure: A review.

Sean Coyne, Kathleen M Gura

Abstract readReview
In one paragraph

Review in Intestinal Failure (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Updates in Intestinal Failure Management.Journal of clinical medicine · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sean CoyneDepartment of Pharmacy, Boston Children's Hospital, Boston, MA, USA.
Kathleen M GuraDepartment of Pharmacy and The Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the hallmark of intestinal failure (IF) management - also known as intestinal rehabilitation - is parenteral nutrition, many of the complications that arise from this complex condition require additional pharmacologic interventions to prevent more serious consequences such as intestinal failure associated liver disease and central line associated bloodstream infections. This brief review highlights some of the more commonly used treatment strategies in pediatric patients with IF along with a review how different types of short bowel anatomy impact drug administration.

Indexed as

Antibiotic lockCentral line associated bloodstream infectionIntestinal failureShort bowel syndromeSmall bowel bacterial overgrowth

Identifiers

PMID41646109
PMCPMC12851206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.