ArticleiGIE : innovation, investigation and insights2023
Endoscopic retrograde appendicitis therapy in adults with uncomplicated acute appendicitis: a systematic review and meta-analysis.
Article in iGIE : innovation, investigation and insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Appendoscope-Assisted Endoscopic Retrograde Appendicitis Therapy Versus Antibiotic Monotherapy for Acute Uncomplicated Appendicitis.Digestive diseases and sciences · 2026Article
- Reduced recurrence rate with a targeted approach in uncomplicated appendicitis treated with endoscopic directWorld journal of gastroenterology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Endoscopic retrograde appendicitis therapy (ERAT) has emerged as a minimally invasive endoscopic alternative to laparoscopic appendectomy in the treatment of acute appendicitis. In this systematic review and meta-analysis, we evaluated the efficacy and safety of ERAT in treating uncomplicated acute appendicitis. Methods: A systematic review of studies in the PubMed/MEDLINE and Cochrane databases was performed through June 2023. Primary outcomes were clinical success rate (defined as resolution in signs and symptoms of appendicitis) and technical success rate (defined as successful placement of a drain or stent within the appendicular orifice or irrigation to relieve appendiceal obstruction). Secondary outcomes were adverse event rates and rates of intestinal perforation, procedure time, hospital length of stay, duration of follow-up, and rates of appendicitis recurrence after ERAT. Results: Eight studies were considered eligible for analysis (326 patients, average age of 36.4 years old, 55.4% men). The rate of technical success was 98% (95% confidence interval [CI], 97-100; Conclusions: ERAT demonstrated excellent technical and clinical success rates with minimal adverse events. Additional randomized controlled studies are needed to refine inclusion criteria and to standardize the approach to appendiceal stent placement during ERAT to minimize rates of intestinal perforation.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.