ArticleiGIE : innovation, investigation and insights2023
Efficacy and safety of submucosal tunneling endoscopic resection for subepithelial tumors in the upper GI tract: a systematic review and meta-analysis of >2900 patients.
Article in iGIE : innovation, investigation and insights, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07411118 (Exposed Endoscopic Full Thickness Resection), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exposed Endoscopic Full Thickness Resection (EFTR) Versus Submucosal Tunnelling Endoscopic Resection (STER) for Small Gastric Gastrointestinal Stromal Tumor (GIST) - an International Double Blinded Randomized Controlled Trial
Who cites it
5 citing papers in PubMed.
- Third-space endoscopy: Current techniques, clinical applications, and future directions.The Journal of international medical research · 2026Review
- Innovations in Advanced Endoscopic Resection of Early Upper Gastrointestinal Cancer.Journal of clinical medicine · 2026Review
- Submucosal Tunneling Endoscopic Resection for Upper Gastrointestinal Subepithelial Lesions: Development of a Digital Nomogram.Endoscopy international open · 2026Article
- Endoscopic calabash technique for gastric mesenchymal tumours: A low hanging fruit or a novel endoscopic technique?World journal of gastrointestinal endoscopy · 2025Article
- Performance of endoscopic submucosal dissection and submucosal tunneling endoscopic resection for esophageal submucosal tumors: A multicenter retrospective cohort study.Annals of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aims: Submucosal tunnel endoscopic resection (STER) is an emerging therapeutic tool that allows direct visualization and resection of submucosal tunneling endoscopic resection (SETs) from the upper GI tract while maintaining the integrity of the mucosa. Our aim was to conduct a systematic review and meta-analysis to evaluate the efficacy and safety of STER in treating all types of SETs found in the upper GI tract. Methods: A comprehensive search of major databases such as PubMed/Medline, Embase, Results: Eighteen studies with 2941 patients were included; the mean age was 49.74 years, and 61.82% were male. Pooled rates for the overall R0 resection, en bloc resection, and AEs were 92.4%, 91.5%, and 17.8%, respectively. However, only 1.2% of AEs were considered severe. The en bloc resection rate for the tumors in the esophagogastric junction layer was lower at 81.5%. The R0 and en bloc resection rates for tumors originating from the muscularis propria layer were also lower (88.3% and 89.1%). Gas-related adverse events were the most frequent AE with a rate of 5.9%. The recurrence rate was 2.3%. Conclusions: Our meta-analysis showed that STER is overall an effective and safe therapeutic modality to remove SETs from the upper GI tract.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.