Evidence map›Paper›PMID 41645885›Full record

Trial reportJournal of hospital medicine2026

A randomized trial of I-SLEEP: A patient education and empowerment intervention on inpatient sleep duration and medical sleep disruptions.

Aashna Sunderrajan, John Cursio, Noah Mason, Maxx Byron, Maylyn Martinez, Nicola Orlov, Kristen L Knutson, Babak Mokhlesi, Valerie G Press, David O Meltzer and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of hospital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04151251 (Mentoring Patient-Oriented Research), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04151251 nacompletednot on this map

Mentoring Patient-Oriented Research: Sleep & Health During & After Hospital Stay

TypeinterventionalSponsorUniversity of ChicagoRan2020 to 2023Enrolled256ConditionsSleepArmsPatient Empowerment, Sleep Kit
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aashna SunderrajanDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-3615-0118
John CursioDepartment of Public Health Sciences, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-2131-1767
Noah MasonDepartment of Pediatrics, University of Colorado, Boulder, Colorado, USA.
Maxx ByronChicago School of Professional Psychology, Chicago, Illinois, USA.
Maylyn MartinezDepartment of Pediatrics, University of Chicago, Chicago, Illinois, USA.
Nicola OrlovDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
Kristen L KnutsonCenter for Circadian and Sleep Medicine, Northwestern University, Evanston, Illinois, USA.
Babak MokhlesiDepartment of Medicine, Rush University, Chicago, Illinois, USA.
Valerie G PressDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
David O MeltzerDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.
Vineet M AroraDepartment of Medicine, University of Chicago, Chicago, Illinois, USA.

Funding

Mentoring Patient-Oriented Research: Sleep & Health During & After Hospital StayK24HL136859 · NHLBI · UNIVERSITY OF CHICAGO · PI ARORA, VINEET · 2017 to 2021
$572k
Racial Differences in Hospital-Associated Disability and Acute and Post-Acute Care Physical Therapy UtilizationK23MD019072 · NIMHD · UNIVERSITY OF CHICAGO · PI Maylyn Martinez · 2023 to 2026
$530k
NHLBI NIH HHS K24 HL136859NHLBI NIH HHS K24HL136859-05NIMHD NIH HHS K23 MD019072
6 · The paper itself

Abstract

backgroundSleep is essential for recovery in hospitalized patients, yet frequent disruptions from medical care make rest difficult. Most prior efforts have focused on environmental modifications, often overlooking patients' role in advocating for their sleep.

objectivesThis study evaluated the effectiveness of the Inpatient Sleep Loss: Educating and Empowering Patients (I-SLEEP) intervention in improving sleep duration and reducing medical care disruptions among hospitalized patients.

methodsIn this single-center randomized controlled trial (NCT04151251), general medicine patients at the University of Chicago were randomized to either I-SLEEP (sleep education, advocacy questions, and a sleep kit) or standard care (sleep kit alone) between July 2019 and March 2023. The primary outcome was patient-reported sleep duration. Secondary outcomes included actigraphy-measured sleep duration and continuity (efficiency and wake after sleep onset), as well as patient-reported sleep disruptions. Mixed effects models adjusted for covariates were used for analysis.

resultsA total of 194 participants were enrolled. There were no significant differences in demographic characteristics between groups. Sleep duration and continuity did not differ significantly between groups. However, patients receiving I-SLEEP reported fewer disruptions from vital sign monitoring (63% vs. 75%, p = .004), medication administration (49% vs. 61%, p = .003), and laboratory draws (57% vs. 68%, p = .009). These findings remained significant after adjusting for covariates.

conclusionsI-SLEEP did not increase sleep duration or continuity but reduced medical care disruptions. These findings suggest that patient education and empowerment may be effective strategies for reducing preventable care-related sleep disruptions in hospitals. Further research should examine implementation at scale and potential long-term benefits.

Indexed as

EmpowermentInpatientsPatient Education as TopicSleep DurationActigraphyAdultAgedFemaleHumansMaleMiddle Aged

Identifiers

PMID41645885
PMCPMC13432472

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.