Evidence map›Paper›PMID 41645785›Full record

ArticleJournal of the American Society for Mass Spectrometry2026

Intramolecularly Labeled Reference Standards of Sulfamethoxazole for Fragment-Specific Isotope Analysis by Electrospray Ionization Orbitrap Mass Spectrometry.

Aoife Canavan, Christopher Dirr, Martin Elsner

Abstract read
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aoife CanavanTUM School of Natural Sciences, Department of Chemistry, Chair of Analytical Chemistry and Water Chemistry, Technical University of Munich, Lichtenbergstraße 4, 85748 Garching, Germany.ORCID 0009-0001-0994-0846
Christopher DirrTUM School of Natural Sciences, Department of Chemistry, Chair of Analytical Chemistry and Water Chemistry, Technical University of Munich, Lichtenbergstraße 4, 85748 Garching, Germany.ORCID 0009-0005-9805-2830
Martin ElsnerTUM School of Natural Sciences, Department of Chemistry, Chair of Analytical Chemistry and Water Chemistry, Technical University of Munich, Lichtenbergstraße 4, 85748 Garching, Germany.ORCID 0000-0003-4746-9052

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widespread presence of pharmaceuticals, including antibiotics, in our aquatic environment raises important societal concerns. When studying their environmental fate, stable isotope analysis of nitrogen and carbon at natural abundance offers unique insight into source fingerprinting and degradation-associated kinetic isotope effects. Here, we synthesized compound-specific reference standards to enable electrospray ionization (ESI) Orbitrap mass spectrometry (MS) for fragment-specific carbon and nitrogen isotope analysis (Δδ

Indexed as

Anti-Bacterial AgentsSpectrometry, Mass, Electrospray IonizationSulfamethoxazoleCarbon IsotopesIsotope LabelingNitrogen IsotopesReference StandardsAnti-Bacterial AgentsCarbon IsotopesNitrogen IsotopesSulfamethoxazoleantibioticscollision-induced fragmentationintramolecular isotope ratiosisotope fractionationisotope standardskinetic isotope effectOrbitrap-IRMSreference materialssulfonamides

Identifiers

PMID41645785
PMCPMC12964526

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.