Initiation of proton pump inhibitors is associated with gut microbiome diversity and composition: a new-user target trial emulation within the Baltimore Longitudinal Study of Aging.
Article in American journal of epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
7 authors.
Bruno BohnLifecourse Epidemiology of Adiposity and Diabetes Center, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States.ORCID 0000-0001-8961-6968
Curtis TilvesLifecourse Epidemiology of Adiposity and Diabetes Center, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States.ORCID 0000-0003-0281-5986
Toshiko TanakaLongitudinal Studies Section, Translational Gerontology Branch, National Institute of Aging, Baltimore, MD, United States.ORCID 0000-0002-4161-3829
Luigi FerrucciLongitudinal Studies Section, Translational Gerontology Branch, National Institute of Aging, Baltimore, MD, United States.ORCID 0000-0002-6273-1613
Chee W ChiaClinical Research Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.ORCID 0000-0003-3218-0141
Adam SpiraDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.ORCID 0000-0003-1507-0995
Noel T MuellerLifecourse Epidemiology of Adiposity and Diabetes Center, University of Colorado, Anschutz Medical Campus, Aurora, CO, United States.ORCID 0000-0002-7412-8352
Funding
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI DANIEL Holland BESSESEN · 1995 to 2026
$32.6M
Poor Sleep Altered Circadian Rhythms and Alzheimers DiseaseR01AG050507 · NIA · JOHNS HOPKINS UNIVERSITY · PI SPIRA, ADAM PETER · 2015 to 2019
$2.5M
Effects of Dietary Patterns and Sodium Intake on the Gut Microbiome and MetabolomeR01HL166473 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI NOEL T MUELLER · 2023 to 2026
$2.4M
Associations of diet trajectories over the adult life course with cardiovascular risk factors, age-related functional declines and mortalityR01AG051752 · NIA · GEORGE WASHINGTON UNIVERSITY · PI TALEGAWKAR, SAMEERA A · 2016 to 2018
$886k
The Effects of Diet on the Gut Microbiome and Short Chain Fatty AcidsK01HL141589 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MUELLER, NOEL T · 2018 to 2022
$845k
Employing smart underwear to measure gut microbial hydrogen sulfide productionR21DK132310 · NIDDK · UNIV OF MARYLAND, COLLEGE PARK · PI GHODSSI, REZA, HALL, ANDREW BRANTLEY · 2022 to 2023
$418k
NHLBI NIH HHS K01 HL141589NHLBI NIH HHS R01 HL166473NIA NIH HHS R01 AG050507NIA NIH HHS R01AG050507, R01AG051752NIA NIH HHS R01 AG051752NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R21 DK132310the American Heart Association 25CDA1447396the National Heart, Lung, and Blood Institute grants K01HL141589 and R01HL166473the National Institute of Diabetes and Digestive and Kidney Diseases (grant R21DK132310the NIA intramural program
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Initiation of proton pump inhibitors is associated with gut microbiome diversity and composition: a new-user target trial emulation within the Baltimore Longitudinal Study of Aging. · full record | OpenQuestion