Evidence map›Paper›PMID 41645345›Full record

ArticleBrain and behavior2026

Examination of the Peripheral Nervous System in Children With Spinal Muscular Atrophy: A High-Resolution Ultrasonographic Study.

Janina Wurster, Erin West, Sandro Meier, Noé Phillip Bürke, Lynn Jansen, Philip Julian Broser

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In one paragraph

Article in Brain and behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Janina WursterChildren's Hospital of Eastern Switzerland, St. Gallen, Switzerland.
Erin WestClinical Trials Unit, HOCH Health Ostschweiz, Kantonsspital St. Gallen, St. Gallen, Switzerland.
Sandro MeierChildren's Hospital of Eastern Switzerland, St. Gallen, Switzerland.
Noé Phillip BürkeChildren's Hospital of Eastern Switzerland, St. Gallen, Switzerland.
Lynn JansenChildren's Hospital of Eastern Switzerland, St. Gallen, Switzerland.
Philip Julian BroserChildren's Hospital of Eastern Switzerland, St. Gallen, Switzerland.

Funding

Canon Medical Systems CorporationOstschweizer KinderspitalStiftung OPOS zugunsten von Wahrnehmungsbehinderten
6 · The paper itself

Abstract

objectivesRecent studies have shown that high-resolution ultrasound (HRUS) devices allow us to accurately measure peripheral nerves in newborns. In consideration of these developments, this study aimed to analyze the structure and cross-sectional area (CSA) of the median nerve in children with SMA and evaluate the usefulness and reproducibility of HRUS imaging for the monitoring of peripheral nerves in these children.

methodsA total of 12 participants aged 1-15 years with SMA were included in this repeated cross-sectional study. In addition, 97 normally developing children aged 2 days to 17 years were included as controls. Using HRUS devices, the structure and CSA of the median nerve were determined at three sites (wrist, forearm, and above the elbow). The measured CSA and nerve structure were compared between the groups.

resultsThe CSA of the median nerve was smaller in the children with SMA than in the controls. Compared to the controls, SMA children had a mean CSA ranging from 0.70 to 1.02 mm

conclusionHRUS is a useful method for monitoring nerve growth in children with SMA.

Indexed as

Median NerveMuscular Atrophy, SpinalPeripheral Nervous SystemAdolescentChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleReproducibility of ResultsUltrasonographycross‐sectional areaHRUSnerve structurespinal muscular atrophy

Identifiers

PMID41645345
PMCPMC12876041

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