Evidence map›Paper›PMID 41645102›Full record

ArticleBMC neurology2026

Favorable seizure control with a gluten-free diet in a patient with drug-resistant epilepsy and celiac disease: a case report.

Hajer Hassine, Fatma Fatnassi, Chaima Jemai, Nesrine Krifa, Habiba Dabbebi, Souhir Monastiri, Haythem Yacoub, Dhouha Cherif, Nadia Maamouri, Hela Kchir

Abstract readCase Reports
In one paragraph

Article in BMC neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Hajer HassineDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.
Fatma FatnassiDepartment of Neurology, National Institute of Neurology, Tunis, Tunisia.
Chaima JemaiDepartment C of therapeutic dietetics, National Institute of Nutrition, 11, Rue Jebel Lakhdar, Bab Saâdoun, Tunis, 1007, Tunisia. chaima.jemai@fmt.utm.tn.
Nesrine KrifaDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.
Habiba DabbebiDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.
Souhir MonastiriDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.
Haythem YacoubDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.
Dhouha CherifDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.
Nadia MaamouriDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.
Hela KchirDepartment of Gastroenterology 'B', La Rabta University Hospital, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCeliac disease (CD) is a chronic autoimmune disorder triggered by gluten sensitivity. Beyond its gastrointestinal presentation, CD is increasingly associated with neurological manifestations, including epilepsy. CASE PRESENTATION: To report the case of a 21-year-old female with a 15-year history of medically resistant epilepsy. Despite multiple antiseizure medications, seizure control remained inadequate. Further evaluation led to a diagnosis of biopsy-confirmed CD. The patient was initiated on a strict gluten-free diet, which resulted in significant clinical improvement and better seizure control. The ethnicity of the patient is Arab-berber (Maghrebi).

conclusionThis case highlights the importance of considering CD in the differential diagnosis of medically resistant epilepsy. Early recognition and dietary management may improve neurological outcomes.

Indexed as

Celiac DiseaseDiet, Gluten-FreeDrug Resistant EpilepsySeizuresFemaleHumansYoung AdultCeliac diseaseComplicationGluten-free dietResistant epilepsySeizure

Identifiers

PMID41645102
PMCPMC12896140

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