Evidence map›Paper›PMID 41645080›Full record

ArticleBMC pregnancy and childbirth2026

Stillbirths in a large Shanghai maternity centre (2014-2024): trends, sex distribution, and gestational age-specific risk.

Rui-Hong Xue, Ying Zhang, Dan Tang, Yun-Xia Li, Juan Li, Lin Zhang

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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Rui-Hong Xue *International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, No.910 Hengshan Road, Shanghai, 200030, China.
Ying Zhang *International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, No.910 Hengshan Road, Shanghai, 200030, China.
Dan TangKaramay Central Hospital, Karamay, 834000, China.
Yun-Xia LiKaramay Central Hospital, Karamay, 834000, China.
Juan LiInternational Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, No.910 Hengshan Road, Shanghai, 200030, China. 13564493411@126.com.
Lin ZhangInternational Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, No.910 Hengshan Road, Shanghai, 200030, China. lilyyulin2003@icloud.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStillbirth is a catastrophic adverse pregnancy outcome that harms families and is a major global public health concern; however, the available data regarding its prevalence, sex disparities, and gestational age distribution (key for targeted interventions) are insufficient. This study addressed this gap in a large Shanghai pregnant cohort.

methodsThis retrospective study included 140,594 pregnant women (after incomplete/nonsingleton cases were excluded) who delivered at a tertiary hospital (Oct 2014–Sep 2024). Stillbirth was defined per the WHO guidelines (≥ 28 weeks). Stillbirth rates were calculated overall and stratified by foetal sex/gestational age (28–31, 32–36, and ≥ 37weeks). Mann‒Kendall test was used to assess trends (2015–2023), chi-square tests were used to compare subgroups, and analyses were performed in R 4.5.1 (P < 0.05 indicates statistical significance).

resultsAmong 140,594 deliveries, 249 stillbirths occurred (rate: 0.18%; 95% CI: 0.16–0.20%). The increasing trend from 2015–2023 was nonsignificant (Z = 0.738, P = 0.461; tau = 0.229), with no sex disparities (males: 51.81%; 129/249; females: 48.19%; 120/249; χ²=0.325; P = 0.5684). Regardless of sex, stillbirths were more common at 28–31 weeks and fewer at ≥ 37 weeks (male: χ²=28.79; female: χ²=21.05; P < 0.001).

conclusionsStillbirth rate in our maternity centre has remained consistently low over the past decade, with no significant temporal increase or sex-based disparities observed. The risk of stillbirth decreased with advancing gestational age, with the highest risk noted at 28–31 weeks; these findings underscore the need for targeted monitoring and interventions during the early phase of late pregnancy. Future multicentre studies are warranted to validate these findings and provide evidence to inform stillbirth prevention strategies.

Indexed as

Gestational AgeStillbirthAdultChinaFemaleHospitals, MaternityHumansMalePregnancyPrevalenceRetrospective StudiesRisk FactorsSex DistributionGestational agePrevalenceSex ratioStillbirth

Identifiers

PMID41645080
PMCPMC13011506

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.