Evidence map›Paper›PMID 41645031›Full record

ArticleBiotechnology and applied biochemistry2026

Synthesis and in Silico Evaluation of Novel Triazolone-Derived Naphthalene-2-Sulfonates, Evaluation of Potential Antiproliferative Agents and Enzyme Inhibitory Activities.

Onur Akyıldırım, Abdülmelik Aras, Ercan Oguz, Alpaslan Bayrakdar, Fikret Türkan, Murat Beytur, Hilal Medetalibeyoğlu, Ercan Bursal, Haydar Yüksek

Abstract read
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In one paragraph

Article in Biotechnology and applied biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Onur AkyıldırımDepartment of Chemical Engineering, Faculty of Engineering and Architecture, Kafkas University, Kars, Türkiye.
Abdülmelik ArasDepartment of Biochemistry, Faculty of Science and Arts, Iğdır University, Iğdır, Türkiye.
Ercan OguzVocational School of Higher Education for Health Services, Igdir University, Iğdır, Türkiye.
Alpaslan BayrakdarVocational School of Higher Education for Health Services, Igdir University, Iğdır, Türkiye.
Fikret TürkanDepartment of Basic Sciences, Faculty of Dentistry, Iğdır University, Iğdır, Türkiye.
Murat BeyturDepartment of Chemistry, Faculty of Science and Letters, Kafkas University, Kars, Türkiye.
Hilal MedetalibeyoğluDepartment of Chemistry, Faculty of Science and Letters, Kafkas University, Kars, Türkiye.
Ercan BursalFaculty of Health Sciences, Mus Alparslan University, Mus, Türkiye.
Haydar YüksekDepartment of Chemistry, Faculty of Science and Letters, Kafkas University, Kars, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports the synthesis and biological evaluation of four novel N-acetyl-derived heterocyclic compounds, namely 2-((1-acetyl-3-substituted-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)iminomethyl)-phenyl-naphthalene-2-sulfonates. The compounds were synthesized via acetylation reactions using acetic anhydride and were fully characterized by IR,

Indexed as

Antineoplastic AgentsEnzyme InhibitorsNaphthalenesTriazolesAcetylcholinesterasealpha-Amylasesalpha-GlucosidasesCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorGlutathione TransferaseHep G2 CellsHumansMolecular Docking SimulationAcetylcholinesterasealpha-Amylasesalpha-GlucosidasesAntineoplastic AgentsEnzyme InhibitorsGlutathione TransferaseNaphthalenesTriazolescytotoxicityenzyme inhibitionmolecular dockingnaphthalene‐2‐sulfonateSchiff base

Identifiers

PMID41645031
PMCPMC13446431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.